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ORIGINAL ARTICLE
Year : 2018  |  Volume : 19  |  Issue : 3  |  Page : 174-177

Corneal collagen cross-linking as an additional step in laser in-situ keratomileusis surgery for preventing post-laser in-situ keratomileusis regression


Ophthalmology Department, Menofia University, Shebin Elkom, Menofia, Egypt

Correspondence Address:
Nermeen M Badawi
FRCS Ophth. (Glasgow), Compound Lake View, 90th Street, Villa 3/1, New Cairo, Cairo 11835
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/DJO.DJO_3_18

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Aim The aim of this study was to evaluate the safety, stability, and efficacy of corneal collagen cross-linking as an additional step in laser in-situ keratomileusis (LASIK) surgery for prevention of post-LASIK regression. Patients and methods Eyes included in this study were classified into two groups: group A consisted of 30 myopic eyes (spherical equivalent between −6.00 and −10.00 D) that underwent LASIK surgery with riboflavin application and ultraviolet light irradiation in the same sitting and group B as the control group which consisted of 30 myopic eyes (spherical equivalent between −6.00 and −10.00 D) that underwent LASIK surgery only without riboflavin application or ultraviolet light irradiation. Postoperative follow-up was at 1 day, 1 week, 1, 3, 6 months, 1, 2, and 3 years postoperatively. Results The mean spherical equivalent at 3 years postoperatively was −0.75 D in group A in comparison with −2.75 D in group B in which the regression started significantly after 1 year postoperatively (from −0.50 to −2.75 D) with less regression (from −0.50 to −0.75 D) in group A by the end of follow-up period (P=0.002). No significant changes in topography or pachymetry were reported in the present study. In addition, no complications related to corneal collagen cross-linking were reported in comparison with the second group. Conclusion Adjuvant use of corneal collagen cross-linking as an additional step in LASIK procedure is safe and effective in decreasing post-LASIK regression.


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