• Users Online: 943
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2019  |  Volume : 20  |  Issue : 2  |  Page : 55-62

Correlation between central corneal thickness and retinal nerve fiber layer thickness in open-angle glaucoma

1 Department of Ophthalmology, Port Said Ophthalmology Specialized Hospital, Port Said, Egypt
2 Department of Ophthalmology, Menoufia University, Shebeen El-Kom, Egypt

Correspondence Address:
Ahmed I Basiony
Department of Ophthalmology, Menoufia University, Shebin El-Kom 72311, Menoufia
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/DJO.DJO_69_18

Rights and Permissions

Background Central corneal thickness (CCT) is an important risk factor in the development and progression of primary open-angle glaucoma (POAG). The retinal nerve fibers respond to high intraocular pressure (IOP) with irreversible loss. So, there is a great interest to study the correlation between these two factors: CCT and retinal nerve fiber layer thickness (RNFLT) using the spectral-domain optical coherence tomography (SD-OCT). Aim The aim of this study was to correlate the CCT and the RNFLT in POAG patients by using SD-OCT. Patients and methods This study was conducted in Menoufia University Hospitals, Egypt, from October 2017 to October 2018. The study included 116 eyes of 61 patients with POAG receiving antiglaucomatous eye drops with controlled IOP. CCT and peripapillary RNFLT were measured by using SD-OCT (Optovue RTVue-100). Then, we performed a correlation between them. Results The study included 61 (40 males and 21 females) patients. The mean age was 51.5±6 years. A significant positive relationship was found between the CCT and the RNFLT (r=0.6). This means that patients with thick cornea have thicker nerve fiber layer than those with thinner corneas. Conclusion CCT is an important risk factor and predictive factor for both diagnosis and prognosis of POAG. So, it is mandatory to be measured to modify the IOP measurements and to correlate with the nerve fiber layer thickness. This helps us to tailor the plan of treatment.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded113    
    Comments [Add]    

Recommend this journal