• Users Online: 501
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2019  |  Volume : 20  |  Issue : 2  |  Page : 82-87

Electrophysiological study of thyroid ocular disorders


1 Depertment ophthalmology, Mansoura Ophthalmic Center, Mansoura Medicine Hospital, Faculty of Medicine, Mansoura University, Mansoura, Egypt
2 Depertment ophthalmology, Mansoura Medicine Hospital, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Correspondence Address:
Mona Abdel Kader
Ophthalmology Center, Faculty of Medicine, Mansoura University, 35516 Mansoura
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/DJO.DJO_50_18

Rights and Permissions

Purpose The aims of this study were to evaluate the visual evoked potential (VEP) changes in thyroid ocular disorders and to correlate between VEP latencies and thyroid hormones. Patients and methods The study participants were divided into four groups. Group 1 comprised 50 patients (100 eyes) with subclinical hypothyroidism (29 patients had recent hypothyroidism without treatment, and 21 patients had controlled hypothyroidism with treatment). Group 2 comprised 35 patients (70 eyes) with overt hypothyroidism (20 patients had recent hypothyroidism without treatment, and 15 patients had controlled hypothyroidism with treatment). Group 3 comprised 35 patients (70 eyes) with hyperthyroidism (18 patients had recent hyperthyroidism without treatment, and 17 patients were under treatment). Group 4 comprised 70 patients (140 eyes) with normal thyroid functions as a control group. Flash and pattern VEP and thyroid hormone assay were performed for all patients. Results There was an increase in the latencies of VEP without statistically significant change in amplitudes in thyroid disorders (groups 1, 2, and 3) compared with the normal control group (group 4). The increase in latencies in group 1 was statistically insignificant (P>0.1), while, in groups 2 and 3, it was statistically significant (P<0.005 and 0.001, respectively). In group 3, there was a positive correlation between latencies and tri-iodothyronine (T3) and thyroxine (T4). The increase in p100 was accompanied with an increase in T3 and T4. Conclusion VEP can detect the early optic nerve defects in the absence of any neurological or ophthalmological symptoms in thyroid disorders.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed110    
    Printed14    
    Emailed0    
    PDF Downloaded16    
    Comments [Add]    

Recommend this journal