• Users Online: 912
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2020  |  Volume : 21  |  Issue : 1  |  Page : 49-56

Choroidal thickness measured by swept source optical coherence tomography in diabetic macular edema


Department of Ophthalmology, Zagazig University, Zagazig, Egypt

Correspondence Address:
Haitham Y Al-Nashar
Department of Ophthalmology, Zagazig University, Zagazig 44519
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/DJO.DJO_32_19

Rights and Permissions

Purpose The aim of this study was to evaluate the choroidal thickness in eyes with diabetic macular edema (DME) with the use of swept source optical coherence tomography (SS-OCT). Patients and methods A total of 240 eyes were included in this prospective nonrandomized study. They were divided into three groups, each including 80 eyes. Group I included patients with DME, group II included diabetic patients without retinopathy, and group III were normal persons. Fluorescein angiography was done for all diabetic patients. Macular and choroidal thicknesses were measured by SS-OCT in all eyes. Forty-five eyes from group I received two intravitreal injections of 0.5 mg/0.05 ml ranibizumab with 1-month interval. Correlation between choroidal and macular thickness was evaluated in eyes with DME. Results The mean choroidal thickness in the central subfield area was 129.7±12.5 μm in group I (eyes with DME), 200.4±2.8 μm in group II (diabetic patients without DME), and 208.3±9.7 μm in group III (normal eyes). There was a statistically significant difference in choroidal thickness between eyes with DME (group I) and both groups II and III (P<0.001), whereas there was no statistically significant difference between diabetic patients without macular edema (group II) and normal participants (group III) (P=0.2). There was no statistically significant difference among the three groups regarding age, refractive errors, and intraocular pressure. The mean best-corrected visual acuity was 0.31±0.09, 0.78±1.1, and 0.84±1.2 in groups I, II, and III, respectively (P=0.001). Negative correlation between macular and choroidal thickness was observed in eyes with DME (r=−0.7, P<0.001). There was no significant difference between choroidal thickness before and after intravitreal injection of ranibizumab (P=0.4). Conclusion Choroidal thickness measured with SS-OCT was decreased in eyes with DME in comparison with normal participants. A negative correlation was observed between choroidal and macular thickness in eyes having DME.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed312    
    Printed27    
    Emailed0    
    PDF Downloaded44    
    Comments [Add]    

Recommend this journal